Search - Institut des Sciences du Médicament Access content directly

Filter your results

419 Results
Domains :

Genetic diversity of VAR2CSA ID1-DBL2Xb in worldwide Plasmodium falciparum populations: Impact on vaccine design for placental malaria

Bita Bordbar , Nicaise Tuikue Ndam , Emmanuelle Renard , Sayeh Jafari-Guemouri , Livingstone Tavul , et al.
Infection, Genetics and Evolution, 2014, 25, pp.81-92. ⟨10.1016/j.meegid.2014.04.010⟩
Journal articles hal-02560676v1

Brain gene therapy for metachromatic leukodystrophy: towards clinical trial

F. Piguet , D. Sondhi , Marie-Anne Colle , Solène Raoul , T. Roujeau , et al.
Human Gene Therapy, 2010, 21 (6), pp.771
Journal articles hal-02659534v1

Brain gene therapy for metachromatic leukodystrophy: towards clinical trial

F. Piguet , D. Sondhi , Marie-Anne Colle , Solène Raoul , T. Roujeau , et al.
9. Annual Congress of the French Society of Cell and Gene Therapy, Jun 2010, Paris, France
Conference papers hal-02823682v1
Image document

Identification of the first intragenic deletion of the PITX2 gene causing an Axenfeld-Rieger Syndrome: case report.

Guillaume de La Houssaye , Ivan Bieche , Olivier Roche , Véronique Vieira , Ingrid Laurendeau , et al.
BMC Medical Genetics, 2006, 7 (2), pp.82. ⟨10.1186/1471-2350-7-82⟩
Journal articles inserm-00121215v1
Image document

Molecular and cellular bases for the protective effects of dopamine D1 receptor antagonist, SCH23390, against methamphetamine-induced neurotoxicity in the rat brain

Geneviève Beauvais
Human health and pathology. Université René Descartes - Paris V; National institutes of health (Etats-Unis), 2012. English. ⟨NNT : 2012PA05P604⟩
Theses tel-00691924v1

Crystal structures of the SH2 domain of grb2: highlight on the binding of a new high-affinity inhibitor

Pierre Nioche , Wang-Qing Liu , Isabelle Broutin , Franck Charbonnier , Marie-Thérèse Latreille , et al.
Journal of Molecular Biology, 2002, 315 (5), pp.1167-1177. ⟨10.1006/jmbi.2001.5299⟩
Journal articles istex hal-02520104v1

Synthesis and in vitro activities of new non-peptidic APA Inhibitors

N. Inguimbert , P. Coric , H. Dhotel , E. Bonnard , C. Llorens-Cortes , et al.
The Journal of Peptide Research, 2005, 65 (2), pp.175-188. ⟨10.1111/j.1399-3011.2004.00211.x⟩
Journal articles istex hal-02461342v1

Novel approaches in the development of new analgesics

Bp Roques , G Gacel , V. Daugé , A Baamonde , G Calenco , et al.
Neurophysiologie Clinique = Clinical Neurophysiology, 1990, 20 (5), pp.369-387. ⟨10.1016/s0987-7053(05)80205-9⟩
Journal articles istex hal-02461566v1

β-Amino-thiols Inhibit the Zinc Metallopeptidase Activity of Tetanus Toxin Light Chain

Loïc M Martin , Fabrice Cornille , Pascale Coric , Bernard P. Roques , Marie-Claude Fournie-Zaluski
Journal of Medicinal Chemistry, 1998, 41 (18), pp.3450-3460. ⟨10.1021/jm981015z⟩
Journal articles istex hal-02461413v1

Relationship between vulnerability to reinforcing effects of morphine and activity of the endogenous cholecystokinin system in Lewis and Fischer rats

Florence Noble , Nadia Benturquia , Dominique Crete , Corinne Canestrelli , Magdalena Mas Nieto , et al.
Addiction Biology, 2012, 17 (3), pp.528 - 538. ⟨10.1111/j.1369-1600.2010.00283.x⟩
Journal articles istex hal-01899923v1

Iminothiol/thiourea tautomeric equilibrium in thiourea lipids impacts DNA compaction by inducing a cationic nucleation for complex assembly

Marie Breton , Michel Bessodes , Serge Bouaziz , Jean Herscovici , Daniel Scherman , et al.
Biophysical Chemistry, 2009, 145 (1), pp.7-16. ⟨10.1016/j.bpc.2009.08.003⟩
Journal articles hal-02122492v1

2,4-Dinitrophenyl 4-Methoxybenzyl Disulfide: A New Efficient Reagent for the Electrophilic Sulfenylation of β-Amino Ester Enolates

Laurent Bischoff , Christelle David , Loïc M Martin , Hervé Meudal , Bernard-Pierre Roques , et al.
Journal of Organic Chemistry, 1997, 62 (14), pp.4848-4850. ⟨10.1021/jo9623853⟩
Journal articles istex hal-02122111v1

Characterization and inhibition of aminopeptidase A by α-mercapto-β-amino acyl dipeptides

Christelle David , Laurent Bischoff , Hervé Meudal , Catherine Llorens-Cortes , Bernard Pierre Roques , et al.
Letters in Peptide Science, 1997, 4 (4/6), pp.411-414. ⟨10.1023/A:1008894115205⟩
Journal articles istex hal-02122127v1
Image document

In Vivo Visualization of Delta Opioid Receptors upon Physiological Activation Uncovers a Distinct Internalization Profile

Lauren Faget , Eric Erbs , Julie Le Merrer , Gregory Scherrer , Audrey Matifas , et al.
Journal of Neuroscience, 2012, 32 (21), pp.7301 - 7310. ⟨10.1523/JNEUROSCI.0185-12.2012⟩
Journal articles hal-01899922v1

Specific Cre/Lox recombination in the mouse proximal tubule.

Isabelle Rubera , Chantal Poujeol , Guillaume Bertin , Lilia Hasseine , Laurent Counillon , et al.
Journal of the American Society of Nephrology, 2004, 15 (8), pp.2050-6. ⟨10.1097/01.ASN.0000133023.89251.01⟩
Journal articles hal-00320804v1

Evidence for Novel Action at the Cell-Binding Site of Human Angiogenin Revealed by Heteronuclear NMR Spectroscopy, in silico and in vivo Studies

Demetra Chatzileontiadou , Aikaterini Tsika , Zoi Diamantopoulou , Jean Delbe , Josette Badet , et al.
ChemMedChem, 2018, 13 (3), pp.259-269. ⟨10.1002/cmdc.201700688⟩
Journal articles hal-02347346v1
Image document

Dynamic Pattern of HOXB9 Protein Localization during Oocyte Maturation and Early Embryonic Development in Mammals

Caroline Sauvegarde , Delphine Paul , Laure Bridoux , Alice Jouneau , Severine S. Degrelle , et al.
PLoS ONE, 2016, 11 (10), pp.e0165898. ⟨10.1371/journal.pone.0165898⟩
Journal articles inserm-02440442v1

The Role of Membranes in the Organization of HIV-1 Gag p6 and Vpr: p6 Shows High Affinity for Membrane Bilayers Which Substantially Increases the Interaction between p6 and Vpr.

Gilmar Salgado , Alexander Vogel , Rodrigue Marquant , Scott Feller , Serge Bouaziz , et al.
Journal of Medicinal Chemistry, 2009, 52 (22), pp.7157-7162. ⟨10.1021/jm901106t⟩
Journal articles hal-02122420v1

Reusable polymer-supported catalyst for the [3+2] Huisgen cycloaddition in automation protocols.

Christian Girard , Esra Onen , Marie Aufort , Sophie Beauvière , Edmond Samson , et al.
Organic Letters, 2006, 8 (8), pp.1689-92. ⟨10.1021/ol060283l⟩
Journal articles inserm-00135914v1
Image document

Regulation of genes involved in dopamine transporter modulation by acute cocaine in rat striatum.

Cindie Courtin , Dominique Crete , Corinne Canestrelli , Florence Noble , Cynthia Marie-Claire
Neuroscience Letters, 2006, 398 (3), pp.235-40. ⟨10.1016/j.neulet.2006.01.001⟩
Journal articles inserm-00162388v1
Image document

Development and validation of an antigen-binding capture ELISA for native and putrescine-modified anti-tetanus F(ab')2 fragments for the assessment of the cellular uptake and plasma kinetics of the antibodies.

Frédéric Welfringer , Philippe d'Athis , Jean-Michel Scherrmann , Françoise Hervé
Journal of Immunological Methods, 2005, 307 (1-2), pp.82-95. ⟨10.1016/j.jim.2005.09.015⟩
Journal articles inserm-00259343v1
Image document

Fos but not Cart (cocaine and amphetamine regulated transcript) is overexpressed by several drugs of abuse: a comparative study using real-time quantitative polymerase chain reaction in rat brain.

Cynthia Marie-Claire , Ingrid Laurendeau , Corine Canestrelli , Cindie Courtin , Michel Vidaud , et al.
Neuroscience Letters, 2003, 345 (2), pp.77-80
Journal articles inserm-00171266v1
Image document

Endothelial cell protein C receptor and the risk of venous thrombosis.

Sophie Gandrille
Haematologica, 2008, 93 (6), pp.812-6. ⟨10.3324/haematol.13243⟩
Journal articles inserm-00286454v1

Putative functional domains of human cytomegalovirus pUL56 involved in dimerization and benzimidazole D-ribonucleoside activity

Gaël Champier , Anthony Couvreux , Sébastien Hantz , Armelle Rametti , Marie-Christine Mazeron , et al.
Antiviral Therapy, 2008, 13 (5), pp.643-654
Journal articles hal-00406828v1
Image document

Modulation of PAPP-A expression by PPARgamma in human first trimester trophoblast.

Karen Handschuh , Jean Guibourdenche , Mickaël Guesnon , Ingrid Laurendeau , Danièle Evain-Brion , et al.
Placenta, 2006, 27 Suppl A, pp.S127-34. ⟨10.1016/j.placenta.2005.10.012⟩
Journal articles inserm-00000053v1
Image document

Differences in transition state stabilization between thermolysin (EC and neprilysin (EC

Cynthia Marie-Claire , Emmanuel Ruffet , Gilles Tiraboschi , Marie-Claude Fournie-Zaluski
FEBS Letters, 1998, 438 (3), pp.215-9
Journal articles inserm-00145191v1
Image document

Human Chorionic Gonadotropin Produced by the Invasive Trophoblast But Not the Villous Trophoblast Promotes Cell Invasion and Is Down-Regulated by Peroxisome Proliferator-Activated Receptor-{gamma}

Karen Handschuh , Jean Guibourdenche , Vassilis Tsatsaris , Mickaël Guesnon , Ingrid Laurendeau , et al.
Endocrinology, 2007, 148 (10), pp.5011-5019. ⟨10.1210/en.2007-0286⟩
Journal articles inserm-00173877v1
Image document

CD36 Deficiency Leads to Choroidal Involution via COX2 Down-Regulation in Rodents.

Marianne Houssier , William Raoul , Sophie Lavalette , Nicole Keller , Xavier Guillonneau , et al.
PLoS Medicine, 2008, 5 (2), pp.e39. ⟨10.1371/journal.pmed.0050039⟩
Journal articles inserm-00258554v1

Comparison of promoter region constructs for in vivo intramuscular expression

Emmanuelle Fabre , Pascal Bigey , Cécile Orsini , Daniel Scherman
Journal of Gene Medicine - PrePrints, 2006, 8 (5), pp.636-645
Journal articles inserm-00193148v1

Effects of chronic morphine and morphine withdrawal on gene expression in rat peripheral blood mononuclear cells

Stephane Desjardins , Emilie Belkai , Dominique Crete , Laurie Cordonnier , Jean-Michel Scherrmann , et al.
Neuropharmacology, 2008, 55 (8), pp.1347 - 1354. ⟨10.1016/j.neuropharm.2008.08.027⟩
Journal articles hal-01905201v1