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Domains : sdv.tox

Mechanisms of respiratory insufficiency induced by methadone overdose in rats

Lucie Chevillard , Bruno Mégarbane , Frédéric Baud , Patricia Risède , Xavier Declèves , et al.
Addiction Biology, 2010, 15 (1), pp.62-80. ⟨10.1111/j.1369-1600.2009.00184.x⟩
Journal articles hal-03823007v1
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Respiratory effects of diazepam/methadone combination in rats: A study based on concentration/effect relationships.

Lucie Chevillard , Xavier Declèves , Frédéric J. Baud , Patricia Risède , Bruno Mégarbane
Drug Alcohol Depend, 2013, epub ahead of print. ⟨10.1016/j.drugalcdep.2012.12.020⟩
Journal articles inserm-00790713v1
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Environmentally friendly expeditious one-pot electrochemical synthesis of bis-catechol-thioether metabolites of ecstasy: in vitro neurotoxic effects in the rat hippocampus

Anne Felim , Anne Neudorffer , François P. Monnet , Martine Largeron
International Journal of Electrochemical Science, 2008, 3 (2), pp.266-281
Journal articles hal-03138868v1

Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)

Nicolas Tournier , Lucie Chevillard , Bruno Megarbane , Stéphane Pirnay , Jean-Michel Scherrmann , et al.
International Journal of Neuropsychopharmacology, 2010, 13 (07), pp.905-915. ⟨10.1017/S1461145709990848⟩
Journal articles hal-03823012v1

Respiratory effects of diazepam/methadone combination in rats: A study based on concentration/effect relationships

Lucie Chevillard , Xavier Declèves , Frédéric Baud , Patricia Risède , Bruno Mégarbane
Drug and Alcohol Dependence, 2013, 131 (3), pp.298-307. ⟨10.1016/j.drugalcdep.2012.12.020⟩
Journal articles hal-03822999v1

Development, validation and clinical application of a LC-MS/MS method for the simultaneous quantification of hydroxychloroquine and its active metabolites in human whole blood

Marion Soichot , Bruno Mégarbane , Pascal Houzé , Lucie Chevillard , Julien Fonsart , et al.
Journal of Pharmaceutical and Biomedical Analysis, 2014, 100, pp.131-137. ⟨10.1016/j.jpba.2014.07.009⟩
Journal articles hal-03822976v1

The large spectrum of pulmonary complications following illicit drug use: Features and mechanisms

Bruno Mégarbane , Lucie Chevillard
Chemico-Biological Interactions, 2013, 206 (3), pp.444-451. ⟨10.1016/j.cbi.2013.10.011⟩
Journal articles hal-03822997v1

Does High-Dose Buprenorphine Cause Respiratory Depression?

Bruno Megarbane , Raymond Hreiche , Stéphane Pirnay , Nicolas Marie , Frédéric J Baud
Toxicological Reviews, 2006, 25 (2), pp.79-85. ⟨10.2165/00139709-200625020-00002⟩
Journal articles hal-02147534v1

Characteristics and comparative severity of respiratory response to toxic doses of fentanyl, methadone, morphine, and buprenorphine in rats

Lucie Chevillard , Bruno Mégarbane , Patricia Risède , Frédéric Baud
Toxicology Letters, 2009, 191 (2-3), pp.327-340. ⟨10.1016/j.toxlet.2009.09.017⟩
Journal articles hal-03823015v1
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Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels

Aude Jacob , Anika Ms Hartz , Sophie Potin , Xavier Coumoul , Salah Yousif , et al.
Fluids and Barriers of the CNS, 2011, 8 (1), pp.23. ⟨10.1186/2045-8118-8-23⟩
Journal articles hal-02190081v1
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Evaluation of drug administration errors in a teaching hospital.

Sarah Berdot , Brigitte Sabatier , Florence Gillaizeau , Thibaut Caruba , Patrice Prognon , et al.
BMC Health Services Research, 2012, 12 (1), pp.60. ⟨10.1186/1472-6963-12-60⟩
Journal articles inserm-00702628v1

Prospective comparative assessment of buprenorphine overdose with heroin and methadone: Clinical characteristics and response to antidotal treatment

Bruno Mégarbane , Anne Buisine , Frédéric Jacobs , Dabor Résière , Lucie Chevillard , et al.
Journal of Substance Abuse Treatment, 2010, 38 (4), pp.403-407. ⟨10.1016/j.jsat.2010.01.006⟩
Journal articles hal-03823001v1
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Case report : quantification of methadone-induced respiratory depression using toxicokinetic/toxicodynamic relationships

Bruno Mégarbane , Xavier Decleves , Vanessa Bloch , Christophe Bardin , Francois Chast , et al.
Critical Care, 2007, 11 (1), pp.R5. ⟨10.1186/cc5150⟩
Journal articles hal-03888329v1

Respiratory effects of buprenorphine/naloxone alone and in combination with diazepam in naive and tolerant rats

Camille Cohier , Lucie Chevillard , Patricia Risède , Olivier Roussel , Bruno Mégarbane
Toxicology Letters, 2014, 228 (2), pp.75-84. ⟨10.1016/j.toxlet.2014.04.009⟩
Journal articles hal-03822996v1