Coronavirus disease 2019 as a particular sepsis: a 2-week follow-up of standard immunological parameters in critically ill patients - Université de Lyon
Journal Articles Intensive Care Medicine Year : 2020

Coronavirus disease 2019 as a particular sepsis: a 2-week follow-up of standard immunological parameters in critically ill patients

Abstract

Since the emergence of coronavirus disease 2019 (COVID-19), the number of patients admitted to ICU has never ceased to rise. While awaiting effective antiviral treatments, the understanding of the appropriate host immune response to a virus totally unknown of immune surveillance is of major importance. At the forefront of immune alterations previously described in COVID-19, patients homogenously present severe lymphopenia [1, 2]. Interestingly, bacterial sepsis also deeply perturbs immune homeostasis by inducing a complex immune response that varies over time and associates a systemic inflammatory response and lymphopenia [3]. The objective of the present study was thus to conduct immune monitoring over the first 15 days in COVID-19 patients admitted to ICU based on markers previously evaluated in bacterial sepsis.
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Dates and versions

hal-02902516 , version 1 (17-09-2024)

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Guillaume Monneret, Martin Cour, Sébastien Viel, Fabienne Venet, Laurent Argaud. Coronavirus disease 2019 as a particular sepsis: a 2-week follow-up of standard immunological parameters in critically ill patients. Intensive Care Medicine, 2020, 46, pp.1764-1765. ⟨10.1007/s00134-020-06123-1⟩. ⟨hal-02902516⟩
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