Coronavirus disease 2019 as a particular sepsis: a 2-week follow-up of standard immunological parameters in critically ill patients
Abstract
Since the emergence of coronavirus disease 2019 (COVID-19), the number of patients admitted to ICU has never ceased to rise. While awaiting effective antiviral treatments, the understanding of the appropriate host immune response to a virus totally unknown of immune surveillance is of major importance. At the forefront of immune alterations previously described in COVID-19, patients homogenously present severe lymphopenia [1, 2]. Interestingly, bacterial sepsis also deeply perturbs immune homeostasis by inducing a complex immune response that varies over time and associates a systemic inflammatory response and lymphopenia [3]. The objective of the present study was thus to conduct immune monitoring over the first 15 days in COVID-19 patients admitted to ICU based on markers previously evaluated in bacterial sepsis.
Domains
Life Sciences [q-bio]Origin | Files produced by the author(s) |
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